理研  環境資源科学研究センター 植物免疫研究グループ
 
 

 
2018
 
Kadota, Y. , Liebrand, T. W., Goto, Y. , Sklenar, J. , Derbyshire, P. , Menke, F. L., Torres, M. , Molina, A. , Zipfel, C. , Coaker, G. and Shirasu, K. (2018), Quantitative phosphoproteomic analysis reveals common regulatory mechanisms between effector‐ and PAMP‐triggered immunity in plants. New Phytol.  doi: 10.1111/nph.15523
 
Wakatake, T., Yoshida, S., Shirasu, K. Induced cell fate transitions at multiple cell layers configure haustorium development in parasitic plants (2018) Development. 145: dev164848 doi: 10.1242/dev.164848
 
Kumarkura, N., Ueno, A., Shirasu, K. (2018) Establishment of a selection marker recycling system for sequential transformation of the plant pathogenic fungus Colletotrichum orbiculare. Molecular Plant Pathology. doi: 10.1111/mpp.12766
 
Ichihashi, Y., Kusano, M., Kobayashi, M., Suetsugu, K., Yoshida, S., Wakatake, T., Kumaishi, K., Shibata, A., Saito, K., and Shirasu, K. Transcriptomic and metabolomic reprogramming from roots to haustoria in the parasitic plant, Thesium chinense. (2018) Plant Cell Physiol 59:724-733.
 
Sato, K., Kadota, Y., Gan, P., Bino, T., Uehara, T., Yamaguchi, K., Ichihashi, I., Maki, N., Iwahori, H., Suzuki, T., Shigenobu, S., Shirasu, K. High-Quality Genome Sequence of the Root-Knot Nematode Meloidogyne arenaria Genotype A2-O. (2018) Genome Announcement. 6: e00519-18.  doi: 10.1128/genomeA.00519-18
 
Asai, S., Furzer, O., Cevik, V., Kim, D. S., Ishaque, N., Goritschnig, S., Staskawicz, B.J.,  Shirasu, K., a and Jones, J.D.G. (2018) A downy mildew effector evades recognition by polymorphism of expression and subcellular localization.  Nature Communications.
 
Cui, S., Wada, S., Tobimatsu, Y., Takeda, Y., Saucet, S.B., Takano, T., Umezawa, T., Shirasu, K., and Yoshida, S. Host lignin composition affects haustorium induction in the parasitic plants Phtheirospermum japonicum and Striga hermonthica. (2018) New Phytologist. 218: 710–723.
 
Spallek, T., Gan, P., Kadota, Y., Shirasu, K. Same tune, different song – Cytokinins as virulence factors in plant-pathogen interactions? (2018) Curr Opin Plant Biol.44:82-87.
 
Gao, L., Narita, K., Kumakura, N., Gan, P., Minami, A., Ozaki, T., Liu, C., Lei, X., Shirasu, K. Oikawa, H. Identification of novel sesterterpenes by the genome mining of phytopathogenic fungi Phoma and Colletotrichum sp. (2018) Tetrahedron Letters. 59: 1136-1139.
 
Uemura, A., *Yamaguchi, N, Xu, Y., Wee, W-Y Ichihashi, Y., Suzuki, T., Shibata, A., Shirasu, K., Ito, T. Regulation of floral meristem activity through the interaction of AGAMOUS, SUPERMAN, and CLAVATA3 in Arabidopsis. (2018) Plant Reproduction. 31: 89-105.
 
Noutoshi Y. and Shirasu, K. A High-Throughput Chemical Screening Method for Inhibitors and Potentiators of Hypersensitive Cell Death Using Suspension Cell Culture of Arabidopsis thaliana. (2018) Plant Chemical Biology: Methods and Protocols. Methods in Molecular Biology. in press
 
Ichihashi, Y., Fukushima, A., Shibata, A., and Shirasu, K. High Impact Gene Discovery: Simple Strand Specific mRNA Library Construction and Differential Regulatory Analysis Based on Gene Co-expression Network. (2018) In: Yamaguchi N. (eds) Plant Transcription Factors. Methods in Molecular Biology, vol 1830. Humana Press, New York, NY. DOI https://doi.org/10.1007/978-1-4939-8657-6_11
 
Azmi, N.S.A. Singkaravanit-Ogawa, S., Ikeda, K., Kitakura, S., Inoue, Y., Narusaka, Y., Shirasu, K., Kaido, M., Mise, K., and Takano, Y. Inappropriate expression of an NLP effector in Colletotrichum orbiculare impairs infection on Cucurbitaceae cultivars via plant recognition of the C-terminal region (2018) Mol. Plant Micro. Int. 31: 101-111.
 
石濱伸明 白須賢 植物微生物相互作用におけるサリチル酸生合成と代謝 (2018) 植物の生長調節 53: 53-59.
 
白須賢 比較ゲノミクスをベースにしたイチゴ炭疽病菌Colletotrichum gloeosporioides種複合体の解析 (2018) 植物防疫 4月号 72: 18-21.
 


2017
 
Spallek, T., Melnyk, C.W., Wakatake, T., Zhang, J., Sakamoto, Y., Kiba, T., Yoshida, S., Matsunaga, S., Sakakibara, H., Shirasu, K. Inter-species hormonal control of host root morphology by parasitic plants. (2017) Proc. Natl. Acad. Sci. USA. 114:5283-5288.
 
Gan, P., Nakata, N., Suzuki, T., Shirasu, K. Markers to distinguish different species of anthracnose fungi identify Colletotrichum fructicola as the predominant virulent species in strawberry plants in the Chiba prefecture of Japan (2017) J. Gen. Plant Path. 83: 14-22.
 
Gan, P., Narusaka, M., Tsushima, A., Narusaka, Y., Takano, Y., Shirasu, K. Draft genome assembly of Colletotrichum chlorophyti, a pathogen of herbaceous plants (2017) Genome Announcement 5:e01733-16
 
Ishida, J.K., Yoshida, S., and Shirasu, K. Quinone oxidoreductase 2 is involved in haustorium development of the parasitic plant Phtheirospermum japonicum. (2017) Plant Signaling & Behavior http://dx.doi.org/10.1080/15592324.2017.1319029.
 
Ishida, J.K., Yoshida, S., Shirasu, K. Haustorium induction assay of the parasitic plant Phtheirospermum japonicum. (2017) Bio-protocol 7: e2260.
 
Xu, B., Cheval, C., Laohavisit, A., Chiasson, D., Hocking, B., Olsson, T., Shirasu, K., Faulkner, C., Gilliham, M. A calmodulin-like protein regulates plasmodesmal closure during bacterial immune responses. (2017) New Phytologist 215: 77–84.
 
Ito, S., Yamagami, D., Umehara, M, Hanada, A., Yoshida, Y., Sasaki, Y., Yajima, S., Kyozuka, J., Ueguchi-Tanaka, M., Matsuoka, M., Shirasu, K., Yamaguchi, S., Asami, T. Regulation of strigolactone biosynthesis by gibberellin signaling. (2017) Plant Physiol 174: 1250-1259.
 
Lopez Raex, J.A., Shirasu, K., Foo, E. Strigolactones in plant interactions: the yin and yang. (2017) Trends in Plant Sci.22: 527–537.
 
Matsui, H., Nomura, Y., Egusa, M., Hamada, T., Hyon, G.-S., Kaminaka, H., Watanabe, Y., Ueda, T., Trujillo, M., Shirasu, K., Nakagami, H. The GYF domain protein PSIG1 dampens the induction of cell death during plant-pathogen interactions (2017) PLoS Genetics. 13: e1007037.
 
市橋泰範、石垣祐二、白須賢 植物と根圏微生物叢との相互作用 (2017) アグリバイオ 1: 13-17.
 
白須 賢 生物間相互作用 (2017) テイツ・タイガー 植物生理学・発生学 原著第6版 23. 生物間相互作用 693-729.
 
 
 


2016
 
Ishida, J. K., Wakatake, T., Yoshida, S., Takebayashi, Y., Kasahara, H., Wafula, E., dePamphilis, C. W., Shigetou N., Shirasu, K. Local auxin biosynthesis mediated by a YUCCA flavin monooxygenase regulates the haustorium development in the parasitic plant Phtheirospermum japonicum. (2016) Plant Cell 28:1795-1814.
 
Yoshida, S., Cui, S., Ichihashi, Y., Shirasu, K.  The haustorium, a specialized invasive organ in parasitic plants. (2016) Annu Rev Plant Biol. 67:643-667.PDF
 
Gan, P., Narusaka, M., Kumakura, N., Tsushima, A., Takano, Y., Narusaka, Y., Shirasu, K. Genus-wide comparative genome analyses of Colletotrichum species reveal specific gene family losses and gains during adaptation to specific infection lifestyles. (2016) Genome Biology and Evolution. 8: 1467-1481.
 
Cui, S., Wakatake, T., Hashimoto, K., Saucet, S.B., Toyooka, K., Yoshida, S. and Shirasu, K. Haustorial hairs are specialized root hairs that support parasitism in the facultative parasitic plant, Phtheirospermum japonicum (2016) Plant Physiol.170: 1492-1503.
 
Saucet, S. B. and Shirasu, K. Molecular parasitic plant-host interactions. (2016) PLoS Pathogens. 12: e1005978
 
Ichimura, K., Shinzato, T., Edaki, M., Yoshioka, H., Shirasu, K. SGT1 contributes to maintaining protein levels of MEK2DD to facilitate hypersensitive response-like cell death in Nicotiana benthamiana. (2016) Physiological and Molecular Plant Pathology. 94: 47-52.
 
Yamada, K., Yamaguchi, K., Shirakawa, T., Nakagami, H., Mine, A., Ishikawa, K., Fujiwara, M., Narusaka, M., Narusaka, Y., Ichimura, K., Kobayashi, Y., Matsui, H., Nomura, Y., Nomoto, M., Tada, Y., Fukao, Y., Fukamizo, T., Tsuda, K., Shirasu, K., Shibuya, N. and Kawasaki, T. The Arabidopsis CERK1-associated kinase PBL27 connects chitin perception to
MAPK activation. (2016) EMBO J. e201694248.

 
Narusaka, M., Toyoda, K., Shiraishi, T., Iuchi, S., Takano, Y., Shirasu, K., Narusaka, Y. Leucine zipper motif in RRS1 is crucial for the regulation of Arabidopsis dual resistance protein complex RPS4/RRS1 (2016) Sci Rep. 6: 18702.
 
若竹崇雅、吉田聡子、白須賢 根寄生植物の寄生メカニズム─ ゲノム解読とモデル実験系の確立で農業被害の撲滅に道. (2016) 生物の科学 遺伝 70 (4) 289-293.
 
石濱伸明、崔 勝媛、白須賢 ”サリチル酸” (2016) 新しい植物ホルモンの科学第3版 浅見忠男、柿本辰男編著 講談社
 
熊倉 直祐, 白須 賢 比較ゲノム解析が拓く炭疽病菌の病原性とその進化 (2016) 植物の生長調節 p144-147.pdf
 
若竹崇雅, 吉田聡子, 白須 賢 (2016) 寄生植物コシオガマの吸器形成機構 BSJ-Review 7:249.
 


2015
 
Asai, S. and Shirasu, K. (2015) Plant cells under siege: plant immune system versus pathogen effectors. Curr Opin Plant Biol 28:1-8.
 
Mutuku, J.M., Yoshida, S., Shimizu, T., Ichihashi, Y., Wakatake., T., Seo, M., Takahashi., A., Shirasu, K. The WRKY45-dependent signaling pathway is required for resistance against Striga parasitism. (2015) Plant Physiol 168:1152-1163.
 
Adachi, H., Nakano, T., Miyagawa., N., Ishihama, N., Yoshioka, M., Katou, Y., Yaeno, T., Shirasu, K., and Yoshioka, H. (2015) WRKY transcription factors phosphorylated by MAPK regulate a plant immune NADPH oxidase in Nicotiana benthamiana Plant Cell 27: 2645-2663.
 
Conn, C. E., Bythell-Douglas, R., Neumann, D., Yoshida, S., Whittington, B., Westwood, J. H., Shirasu, K., Bond, C. S. Dyer, K. A., Nelson, D. C. (2015) Convergent evolution of strigolactone perception enabled host detection in parasitic plants. Science 349: 540-543.
 
Ichihashi, Y., Mutuku, J.M., Yoshida, S., and Shirasu, K. (2015) Transcriptomics exposes the uniqueness of parasitic plants. Briefings in Functional Genomics 14: 275-282.
 
Kadota, Y., Shirasu, K. and Zipfel, C. Regulation of the NADPH oxidase RBOHD during plant immunity. (2015) Plant Cell Physiol..56: 1472-1480
 
Mutuku, J.M., Spallek, T., Shirasu, K. Striga: physiology, effects, and genomics. (2015) YEARBOOK OF SCIENCE & TECHNOLOGY 312-314.
 
Asai, S, Shirasu, K, Jones, J. D.G.  Hyaloperonospora arabidopsidis (Downy Mildew) infection Assay in Arabidopsis. (2015)  Bio-protocol 5: e1627.
 
浅井修太、白須賢 植物と病原微生物の相互作用と作物保護 ”難培養微生物研究の最新技術II-微生物の生き様に迫り課題解決へ" (2015) シーエムシー出版 125-134


2014
 
Kadota, Y., Jan Sklenar, J., Derbyshire, P., Stransfeld, L., Asai, S., Ntoukakis, V., Jones, J.D.G., Shirasu, K., Menke, F., Jones, A., and Zipfel, C. Direct regulation of the NADPH oxidase RBOHD by the PRR associated kinase BIK1 is required for ROS burst and plant immunity. (2014) Mol. Cell 54: 43-55.
 
Yoshimoto, K., Shibata, M., Kondo, M., Oikawa, K., Sato, M., Toyooka, K. Shirasu, K, Nishimura, M. and Ohsumi, Y Quality control of plant peroxisomes in organ specific manner via autophagy (2014) J. Cell Sci 127: 1161-1168..
 
Kondo, Y., Ito, T., Nakagami, N., Hirakawa, Y., Saito, M., Tamaki, T., Shirasu, K., and Fukuda, H.. Plant GSK3 proteins regulate xylem cell differentiation downstream of TDIF-TDR signalling. (2014) Nat Commun 5:3504.
 
Masclaux-Daubresse, C., Clément, G., Anne, P., Routaboul, J. M., Guiboileau, A., Soulay, F., Shirasu, K., and Yoshimoto, K. Stitching together the multiple dimensions of autophagy using metabolomics and transcriptomics reveals new impacts on metabolism, development and plant responses to the environment. (2014) Plant Cell 26: 1857-1877.
 
Asai, S., Rallapallia, G., Piquereza, S. J.M., Caillauda, M.-C., J. Furzera, O. J., Ishaquea, N., Wirthmueller, L., Fabroa, G., Shirasu, K., and Jones, J.D.G.. Expression profiling during Arabidopsis/downy mildew interaction reveals a highly-expressed effector that attenuates responses to Salicylic Acid (2014) PLoS Pathogen 10: e1004443.
 
Narusaka, M., Hatakeyama, K., Shirasu, K., and Narusaka, Y., Arabidopsis dual resistance proteins, both RPS4 and RRS1, are required for resistance to bacterial wilt in transgenic Brassica crops (2014) Plant Sig & Behavior. 9: e29130
 
Crouch, J., O’Connell, R., Gan, P., Buiate, E., Torres, M.F., Beirn, L., Shirasu, K., Vaillancourt, L. The Genomics of Colletotrichum. (2014) in R. A. Dean et al. (eds.), Genomics of Plant-Associated Fungi: Monocot Pathogens, Springer-Verlag Berlin Heidelberg, 69-102.
 
Sasaki-Sekimoto, Y., Saito, H., Masuda, S., Shirasu, K., and Ohta, H. Comprehensive analysis of protein interactions between JAZ proteins and bHLH transcription factors that negatively regulate jasmonate signaling. (2014) Plant Sig & Behavior 9: e27639
 
Yi, S. Y., Shirasu, K., Moon, J. S., Lee, S.-G. and Kwon, S.-Y. The activated SA and JA signaling pathways have an
influence on flg22-tiiggered oxidative burst and callose deposition. (2014) PLOS ONE 9: e88951.

 
Yoshida, Y., Wakatake, T., and Shirasu, K. A molecular view of survival strategies of root parasitic plants (2014) Regulation of Plant Growth & Environment. 49: 66-73 (in Japanese).
 
Nakaminami, K., Matsui, A., Nakagami, H., Minami, A., Nomura, Y., Tanaka, M., Morosawa, T., Ishida, J., Takahash, S., Uemura, M., Shirasu, K., and Seki, Analysis of differential expression patterns of mRNA and protein during cold- and de-acclimation in Arabidopsis. (2014) Mol Cell Proteomics 13: 3602-3611.
 


2013
 
Lyons, R., Iwase, A., Gänsewig, T., Sherstnev, A., Duc, C., Barton, G.J., Hanada, K., Higuchi-Takeuchi, M., Matsui, M., Sugimoto, K., Kazan, K., Simpson, G.G., and Shirasu, K. The RNA-binding protein FPA regulates flg22-triggered defense responses and transcription factor activity by alternative polyadenylation. (2013) Scientific Reports.3:2 866
 
Sasaki-Sekimoto, Y., Jikumaru, Y., Obayashi, T., Saito, H., Masuda, S., Kamiya, Y., Ohta, Y., and Shirasu, K. bHLH transcription factors JA-ASSOCIATED MYC2-LIKE 1, JAM2 and JAM3 are negative regulators of jasmonate responses in Arabidopsis (2013) Plant Physiol 163: 291-304.
 
Gan, P., Ikeda, K., Irieda, H., Narusaka, M., O’Connell, R.J., Narusaka, Y., Takano, Y., Kubo, Y., Shirasu, K. Comparative genomic and transcriptomic analyses reveal the hemibiotrophic stage shift of Colletotrichum fungi. (2013) New Phytologist 197:1236-1249.
 
Narusaka, M., Kubo, Y., Hatakeyama, K., Imamura, J., Ezura, H., Nanasato, Y., Tabei, Y., Takano, Y., Shirasu, K., and Narusaka, Y.. Interfamily transfer of dual NB-LRR genes confers resistance to multiple pathogens. (2013) PLOS ONE 8: e55954
 
Spallek, T., Mutuku, M., and Shirasu, K. The genus Striga: a witch profile. (2013) Mol Plant Path 14:861-869
 
Hiruma, K., Fukunaga, S., Bednarek, P., Piślewska-Bednarek, M., Watababe, S., Narusaka, Y., Shirasu, K., and Takano, Y. Glutathione and tryptophan metabolism are required for Arabidopsis immunity during the hypersensitive response to hemibiotrophs. (2013) Proc. Natl. Acad. Sci. USA. 110: 9589-9594.
 
Hashimoto-Sugimoto, M., Higaki, T., Yaeno, T., Nagami, A., Irie, M., Fujimi, M., Miyamoto, M., Akita, K., Negi, J., Shirasu, K., Hasezawa, S., and Iba, K. A Munc13-like protein in Arabidopsis mediates H+-ATPase translocation that is essential for stomatal responses (2013) Nat Comm 4: 2215.
 
Yaeno, T and Shirasu, K. The RXLR motif of oomycete effectors is not a sufficient element for binding to phosphatidylinositol monophosphates Plant Sig & Behavior (2013) 8: e23865
 
Narusaka, M., Kubo, Y., Hatakeyama, K., Imamura, J., Ezura, H., Nanasato, Y., Tabei, Y., Takano, Y., Shirasu, K., and Narusaka, Y. Breaking restricted taxonomic functionality by dual resistance genes. (2013) Plant Signal & Behavior 8: e24244.


 
 
2012
 
Yoshida, S., Kameoka, H., Tempo, M., Akiyama, K., Umehara, M., Yamaguchi, S., Hayashi, H., Kyozuka, J., and Shirasu, K. The D3 F-box protein is a key component in host strigolactone responses essential for arbuscular mycorrhizal symbiosis (2012) New Phytologist 196: 1208-1216
 
Noutoshi, Y., Okazaki, M., Kida, T., Nishina, Y., Morishita, Y., Ogawa, T., Suzuki, S., Shibata, D., Jikumaru, Y., Hanada, A., Kamiya, Y., and Shirasu, K. Novel plant immune-priming compounds identified via high-throughput chemical screening target salicylic acid glucosyltransferases in Arabidopsis (2012) Plant Cell 24:3795-3804.
 
O'Connell R.J. et. al., Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses (2012) Nature Genetics 44:1060-1065.
 
Stegmann, M., Anderson, R.G., Ichimura, K., Pecenkova, T., Reuter, P., Zarsky, V., McDowell, J.M., Shirasu, K., and Trujillo, M. The Ubiquitin Ligase PUB22 Targets a Subunit of the Exocyst Complex Required for PAMP-Triggered Responses in Arabidopsis. (2012) Plant Cell 24:4703-4716.
 
Kadota, Y. and Shirasu, K. The HSP90 complex of plants (2012) Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823: 689–697.
 
Yoshida, S. and Shirasu, K. Plants that attack plants: molecular elucidation of plant parasitism. (2012) Curr Opin Plant Biol 15:708-713
 
Ronald, P. and Shirasu, K. Front-runners in plant–microbe interactions (2012) Curr Opin Plant Biol 15:345-348.
 
Nakagami, H., Sugiyama, N., Ishihama, Y., and Shirasu, K. Shotguns in the front line: Phosphoproteomics in plants (2012) Plant Cell Physiol 53: 118-124.
 
Win, J., Krasileva, K.V., Kamoun, S., Shirasu, K. Staskawicz, B.J., Banfield, M.J. Sequence divergent RXLR effectors share a structural fold conserved across plant pathogenic oomycete species. (2012) PLoS Pathogens 8: e1002400.
 
Noutoshi, Y., Jikumaru, Y., Kamiya, Y., and Shirasu, K. ImprimatinC1, a novel plant immune-priming compound, functions as a partial agonist of salicylic acid. (2012) Scientific Reports 2:705
 
Noutoshi, Y., Ikeda, M., and Shirasu, K. Diuretics prime plant immunity in Arabidopsis thaliana. (2012) PLOS One 7(10): e48443.
 
Noutoshi, Y., Ikeda, M., Saito, T., Osada, H., Shirasu, K. Sulfonamides identified as plant immune-priming compounds in high-throughput chemical screening increase disease resistance in Arabidopsis thaliana (2012) Front. Plant Sci. 3:245
 
Noutoshi, Y., Okazaki, M., and Shirasu, K. Isolation and characterization of plant immune-priming compounds ImprimatinB3 and-B4, potentiators of disease resistance response in Arabidopsis thaliana (2012) Plant Sig & Behavior 7:1526-1528.
 
Noutoshi, Y., Okazaki, M., and Shirasu, K. ImparimatinA and B, novel plant activators targeting metabolism of salicylic acid in Arabidopsis thaliana (2012) Plant Sig & Behavior 7:1715-1717.
 
Narusaka, M., Ohtani, M., Demura, T., Shimada, R., Shirasu, K., Narusaka, Y. Development of a model system comprising Populus as a model tree and Colletotrichum species as a model pathogen for studying host–pathogen interaction (2012) Plant Biotechnology 29: 511-514.
 
Yoshimoto, K., Noutoshi, Y., Hayashi, K., Shirasu, K., Takahashi, T. and Motose, H. A Chemical Biology Approach Reveals an Opposite Action between Thermospermine and Auxin in Xylem Development in Arabidopsis thaliana (2012) Plant Cell Physiol. 53:635-645.
 
Nakayama, M., Kaneko, Y., Miyazawa, Y. Fujii, N., Higashitani, N., Wada, S., Ishida, H., Yoshimoto, K., Shirasu, K., Yamada, K., Nishimura, M., and Takahashi, H. A possible involvement of autophagy in amyloplast degradation in columella cells during hydrotropic response of Arabidopsis roots (2012) Planta. 236:999-1012.
 
Yoshimoto, K., Noutoshi, Y., Hayashi, K., Shirasu, K., Takahashi, T, and Motose, H. Thermospermine suppresses auxin-inducible xylem differentiation in Arabidopsis thaliana (2012) Plant Signal Behavior 7:937-939.
 
八丈野孝, 白須賢 植物のU-box型ユビキチンリガーゼ (2012) 生化学 84:425-431.
 


 
 
2011
 
Yaeno, T., Li, H., Chaparro-Garcia, A., Schornack, S., Koshiba, S., Watanabe, S., Kigawa, T., Kamoun, S., and Shirasu, K. Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity. (2011) Proc. Natl. Acad. Sci. USA. 108: 14682-14687.
 
Ishida, J.K., Yoshida, S., Ito, M., Namba, S. and Shirasu, K. Agrobacterium rhizogenes-mediated transformation of the parasitic plant Phtheirospermum japonicum. (2011) PLoS One 6: e25802.
 
Mashiguchi, K., Tanaka, K., Sakai, T., Sugawara, S., Kawaide, H., Natsume, M., Hanada, H., Yaeno, T., Shirasu, K. Yao, H. McSteen, P., Zhao, Y., Hayashi, K., Kamiya, Y., Kasahara, H. The main auxin biosynthesis pathway in Arabidopsis (2011) Proc. Natl. Acad. Sci. USA. 45: 18512-18517.
 
Ohkama-Ohtsu, N., Sasaki-Sekimoto, Y., Oikawa, A., Jikumaru, Y., Shinoda, S., Inoue, E., Kamide, Y., Yokoyama, T., Hirai, Y., Shirasu, K., Kamiya, Y., Oliver, D.J., and Saito, K. 12-Oxo-phytodienoic acid–Glutathione Conjugate is Transported into the Vacuole in Arabidopsis. (2011) Plant Cell Physiol 52: 205-209.
 
吉田聡子、白須賢 宿主植物から寄生植物への遺伝子水平伝播の発見 (2011) 化学と生物 49: 518-519
 
門田康弘、白須賢 動植物共通の免疫センサーの制御に働くタンパク質複合体 (2011) 科学と生物 49: 154-156.
 


 
 
2010
 
Zhang M.*, Kadota Y.*, Prodromou C., Shirasu K.#, and Pearl L. H.# Structural Basis for Assembly of Hsp90-Sgt1-CHORD Protein Complexes: Implications for Chaperoning of NLR Innate Immunity Receptors. (2010) Molecular Cell 39:269-281.
*These authors contributed equally to this work. #Co-corresponding authors.
 
Yoshida S., Maruyama S., Nozaki H., and Shirasu K. Horizontal Gene Transfer by the Parasitic Plant Striga hermonthica. (2010) Science 328:1128
 
Yoshida S., Ishida J. K., Kamal N. M., Ali A. M., Namba S. and Shirasu K. A full-length enriched cDNA library and expressed sequence tag analysis of the parasitic weed, Striga hermonthica. (2010) BMC Plant Biol. 10:55
 
Nakagami H.*, Sugiyama N.*, Mochida K., Daudi A., Yoshida Y., Toyoda T., Tomita M., Ishihama Y. and Shirasu K. Large-scale comparative phosphoproteomics identifies conserved phosphorylation sites in plants. (2010) Plant Physiol. 153:1161-1174.
*These authors contributed equally to this work.
 
Trujillo M. and Shirasu K. Ubiquitination in plant immunity. (2010) Curr. Opin. in Plant Biol. 13:402-408.
 
Kadota Y., Shirasu K. and Guerois R. NLR sensors meet at the SGT1HSP90 crossroad. (2010) Trends in Biochem. Sci. 35:199-207.
 
Tameling, W.I.L., Nooijena, C., Ludwig, N., Boter, M, Slootweg, E., Goverse, A., Shirasu, K., Joosten, M.H.A.J. RanGAP2 Mediates Nucleocytoplasmic Partitioning of the NB-LRR Immune Receptor Rx in the Solanaceae, Thereby Dictating Rx Function (2010) Plant Cell 22: 4176-4194
 
Kwon S. I., Cho H. J., Jung J. H., Yoshimoto K., Shirasu K., Park O. K. The Rab GTPase RabG3b functions in autophagy and contributes to tracheary element differentiation in Arabidopsis. (2010) Plant J. 64:151-164. 
 
白須賢 吉田聡子 植物を襲う植物ー寄生植物ストライガとの攻防(2010) 遺伝 64: 46-51. 
 
2009
 
Yoshimoto K., Jikumaru Y., Kamiya Y., Kusano M., Consonni C., Panstruga R., Ohsumi Y. and Shirasu K. Autophagy Negatively Regulates Cell Death by Controlling NPR1-Dependent Salicylic Acid Signaling during Senescence and the Innate Immune Response in Arabidopsis. (2009) Plant Cell 21:2914-2927.
 
Narusaka M., Shirasu K., Noutoshi Y., Kubo Y., Shiraishi T., Iwabuchi M. and Narusaka Y. RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens. (2009) Plant J. 60:218-226.
 
Yoshida, S. and Shirasu, K. Multiple layers of incompatibility to the parasitic witchweed, Striga hermonthica. (2009) New Phytologist 183:180-189.
 
Shirasu, K. The HSP90-SGT1 Chaperone Complex for NLR Immune Sensors. (2009) Annual Review of Plant Biology 60:139-164
 
 
2008
 
Kadota, Y., Amigues, B., Ducassou, L., Madaoui, H., Ochsenbein, F., Guerois, R.# and Shirasu, K.# Structural and functional analysis of SGT1-HSP90 core complex required for innate immunity in plants. (2008) EMBO reports 9:1209-1215.
#Co-corresponding authors.
 
Zhang, M., Boter, M., Li, K., Kadota, Y., Panaretou, B., Prodromou, C., Shirasu, K.# and Pearl, L.# Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes. (2008) EMBO J. 27:2789-2798.
#Co-corresponding authors.
 
Trujillo, M., Ichimura, K., Casais, C. and Shirasu, K. Negative regulation of PAMP-triggered immunity by E3 ubiquitin ligase triplet in Arabidopsis. (2008) Current Biology 18:1396-1401.
 
Umehara, M., Hanada, A., Yoshida, S., Akiyama, K., Arite, T., Takeda-Kamiya, N., Magome, H., Kamiya, Y., Shirasu, K., Yoneyama, K., Kyozuka, J. and Yamaguchi, S. Inhibition of shoot branching by new terpenoid plant hormones. (2008) Nature 455:195-200.
 
Nakashima, A., Chen, L., Thao, N.P., Fujiwara, M., Wong, H.L., Kuwano, M., Umeura, K., Shirasu, K., Kawasaki, T and Shimamoto K. RACK1 functions in rice innate immunity by interacting with the Rac1 immune complex. (2008) Plant Cell 20:2265-2279.
 
Sugiyama, N.*, Nakagami, H.*, Mochida, K., Daudi, A., Tomita, M., Shirasu, K.# and Ishihama, Y.# Large-scale phosphorylation mapping reveales the extent of tyrosine phosphorylation in Arabidopsis. (2008) Molecular Systems Biology 4:193 PubMed
*These authors contributed equally to this work.
#Co-corresponding authors.
 
 
Yamaguchi, S., Umehara,M., Hanada, A.,, Yoshida,S Shirasu, K. Method for controlling root parasitic plants US PATENT US 8633356 B2
 
2007
 
Thao, N.P., Chen, L., Nakashima, A., Hara, S., Umemura, K., Takahashi, A., Shirasu, K., Kawasaki, T. and Shimamoto, K. RAR1 and HSP90 form a complex with Rac/Rop GTPase and function in innate-immune responses in rice. (2007) Plant Cell 19:4035-4045.
 
Miya, A., Albert, P., Shinya, T., Desaki, Y., Ichimura, K., Shirasu, K., Narusaka, Y., Kawakami, N., Kaku, H and Shibuya, N. CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis. (2007) Proc. Natl. Acad. Sci. 104:19613-19618.
 
Boter, M., Amigues, B., Peart, J., Breuer, C., Kadota, Y., Casais, C., Moore, G., Kleanthous, C., Ochsenbein, F., Shirasu, K.# and Guerois, R.# Structural and functional analysis of SGT1 reveals that its interaction with HSP90 is required for the accumulation of Rx, an R protein involved in plant immunity. (2007) Plant Cell 19:3791-3804.
#Co-corresponding authors.
 
Nyarko, A., Mosbahi, K.,Rowe, A.J., Leech, A., Boter, M., Shirasu, K. and Kleanthous, C. TPR-mediated self-association of plant SGT1. (2007) Biochemistry 46:11331-11341.
 
Nakagami, H. and Shirasu, K. Purification method of ubiquitinated protein using ubiquitin-binding domain. (2007) Biotechnology Journal 7: 594-598. Review. Japanese.
 
Kadota, Y., Noutoshi, Y. and Shirasu, K. Disease resistance protein complexes in plants. (2007) Tanpakushitsu Kakusan Koso 52: 717-723. Review. Japanese.
 
Maor, R., Jones, A., Nuhse, T.S., Studholme, D.J., Peck, S.C. and Shirasu, K. MudPIT analysis of ubiquitinated proteins in plants. (2007) Molecular & Cellular Proteomics 6(4):601-610. PubMed PDF supplemental data
 
Heise, C.T., Duff, C.S., Boter, M., Casais, C., Airey, J.E., Leech, A.P., Amigues, B., Guerois, R., Moore, G.R., Shirasu, K. and Kleanthous, C. Biochemical characterization of RAR1 cycteine- and histidine-rich domains (CHORDs): A novel class of zinc-dependent protein-protein interaction modules. (2007) Biochemistry 46:1612-1623.
 
邦文 門田康弘, 能年義輝, 白須賢 抵抗性蛋白質複合体 (2007) 蛋白質 核酸 酵素 52: 717-723.
 
2006
 
Ichimura, K., Casais, C., Peck, S.C., Shinozaki, K. and Shirasu, K. MEKK1 is required for MPK4 activation and regulates tissue specific and temperature dependent cell death in Arabidopsis. (2006) J. Biol. Chem. 281:36969-36976.
 
Ichimura, K., Noutoshi, Y. and Shirasu, K. Role of MAP kinase cascade in plant immunity. (2006) Kagaku to Seibutsu 44:466-471. Review. Japanese.
 
Noutoshi, Y., Kuromori, T., Wada, T., Hirayama, T., Kamiya, A., Imura, Y., Yasuda, M., Nakashita, H., Shirasu, K. and Shinozaki, K. Loss of NECROTIC SPOTTED LESIONS 1 associates with cell death and defense responses in Arabidopsis thaliana. (2006) Plant Mol. Biol. 62:29-42.
 
Noutoshi, Y., Ichimura, K. and Shirasu, K. Molecular mechanisms of plant disease resistance protein. (2006) Tanpakushitsu Kakusan Koso 51: 408-418. Review. Japanese.
 
Azevedo, C., Betsuyaku, S., Peart, J., Takahashi, A., Noel, L., Sadanandom, A., Casais, C., Parker, J. and Shirasu, K. Role of SGT1 in resistance protein accumulation in plant immunity. (2006) EMBO J. 25: 2007-2016.
 
Gonzalez-Lamothe, R., Tsitsigiannis, D.I., Ludwig, A.A., Panicot, M., Shirasu, K. and Jones, J.D. The U-Box protein CMPG1 is required for efficient activation of defense mechanisms triggered by multiple resistance genes in tobacco and tomato. (2006) Plant Cell 18: 1067-1083.
 
2005
 
Noutoshi, Y., Ito, T., Seki, M., Nakashita, H., Yoshida, S., Marco, Y., Shirasu, K. and Shinozaki, K. A single amino acid insertion in the WRKY domain of the Arabidopsis TIR-NB-LRR-WRKY type disease resistance protein SLH1 (sensitive to low humidity 1) causes constitutive activation of defense responses and hypersensitive cell death. (2005) Plant J. 43: 873-888.
 
Hein, I., Barciszewska-Pacak, K., Hrubikova, K., Williamson, S., Dinesen, M., Soenderby, I., E., Sundar, S., Shirasu, K. and Lacomme, C. VIGS-based functional characterization of genes associated to powdery mildew resistance in barley. (2005) Plant Physiol. 138: 2155-2164.
 
Maor, R. and Shirasu K. The arms race continues: Battle strategies between plants and fungal pathogens. (2005) Curr. Opin. Microbiol. 8: 399-404.
 
2004
 
Bieri, S., Mauch, S., Shen, Q-H., Peart, J., Devoto, A., Casais, C., Ceron, F., Schulze, S., Steinbis H-H., Shirasu, K. and Schulze-Lefert, P. RAR1 positively controls steady state levels of barley MLA resistance protein and enables sufficient MLA6 accumulation for effective resistance. (2004) Plant Cell 16: 3480-3495.
 
Sadanandom, A., Findlay, K., Doonan, J. H., Schulze-Lefert, P. and Shirasu, K. CHPA, a CHORD containing protein contributes to maintenance of the diploid state in Aspergillus nidulans. (2004) Eukaryot. Cell 3: 984-991.
 
Takahashi, A., Ichimura, K. and Shirasu, K. Functional analysis of proteins essential for plant disease resistance (2004) in Plant Disease Resistance: A New Frontier in Plant Science 2nd edition ed. by Shimamoto, K. (in Japanese): 96-102. SYUJYUNSYA, Tokyo.
 
2003
 
Sullivan, J. A., Shirasu, K. and Deng X. W. The diverse roles of Ubiquitin and the 26S proteasome in the life of plants. (2003) Nat. Rev. Genet. 4:948-958.
 
Hubert, D. A., Tornero, P., Belkhadir, Y., Krishna, P., Takahashi, A., Shirasu, K. and Dangl, J. L. Cytosolic HSP90 associates with and modulates the Arabidopsis RPM1 plant disease resistance protein. (2003) EMBO J. 22: 5679-5689.
 
Takahashi, A., Casais, C., Ichimura, K. and Shirasu, K. HSP90 interacts with RAR1 and SGT1, and is essential for RPS2-mediated disease resistance in Arabidopsis. (2003) Proc. Acad. Natl. Sci. U.S.A.100(20): 11777-11782.
 
Devoto, A., Muskett, P and Shirasu, K. Role of ubiquitination in regulation of plant defense against pathogens. (2003) Curr. Opin. Plant Biol. 6(4): 307-311.
 
Shirasu, K. and Schulze-Lefert, P. Complex formation, promiscuity, and multi-functionality: protein interactions in disease resistance pathways. (2003) Trends Plant Sci. 8: 252-258.
 
Shen, Q., Zhou, F., Bieri, S., Haizel, H., Shirasu, K. and Schulze-Lefert, P. Recognition specificity and RAR1/SGT1 dependency in barley Mla disease resistance alleles to the powdery mildew fungus. (2003) Plant Cell 15: 732-744.
 
2002
 
Toyoda, K., Collins, N. C., Takahashi, A. and Shirasu, K. Resistance and susceptibility of plants to fungal pathogens. (2002) Transgenic Res. 11: 567-582.
 
Peart, J. R., Lui, R., Sadanandom, A., Malcuit, I., Moffett, P., Brice, D. C., Schauser, L., Jaggard, D. A.W., Xiao, S., Coleman, M. J., Dow, M., Jones, J. D.G., Shirasu, K. and Baulcombe D. C. The ubiquitin ligase-associated protein SGT1 is required for host and nonhost disease resistance in plants. (2002) Proc. Acad. Natl. Sci. U.S.A. 99: 10865-10869.
 
Tornero, P., Merritt, P., Sadanandom, A., Shirasu, K., Innes, R. and Dangl, J.L. RAR1 and NDR1 contribute quantitatively to disease resistance in Arabidopsis and their relative contributions are dependent on the R gene assayed (2002) Plant Cell 14(5): 1005-1015.
 
Muskett, P. J., Kahn, K., Austin, M. J., Moisan, L. J., Sadanandom, A., Shirasu, K., Jones, J. D. G. and Parker, J. E. Arabidopsis RAR1 exerts rate-limiting control of R gene-mediated defences against multiple pathogens. (2002) Plant Cell 14: 979-992.
 
Azevedo, C., Sadanandom, A., Kitagawa, K., Freialdenhoven, A., Shirasu, K.# and Schulze-Lefert, P. The RAR1 interactor SGT1, an essential component of R-gene triggered disease resistance. (2002) Science 295: 2073-2076.
#Corresponding author.
 
Peart, J. R. and Shirasu K. To degrade or not to degrade: The emerging question in plant disease resistance. (2002) Physiol. Mol. Plant. Pathol. 61: 73-76.
 
2001
 
Azevedo, C., Santos Rosa, M.-J. and Shirasu, K. The U-box protein family in plants. (2001) Trends Plant Sci. 6: 354-358.
 
2000
 
Shirasu, K. and Schulze-Lefert, P. Regulators of cell death in disease resistance. (2000) Plant Mol. Biol. 44: 371-385.
 
Shirasu, K., Schulman, A. H., Lahaye, T. and Schulze-Lefert, P. A contiguous 66-kb barley DNA sequence provides evidence for reversible genome expansion. (2000) Genome Res. 10: 908-915.
 
1999
 
Shirasu, K. Molecular mechanisms of plant disease resistance. (1999) Tanpakushitsu Kakusan Koso 44: 2331-2337. Japanese.
 
Shirasu, K., Lahaye, T., Tan, M.-W., Zhou, F., Azevedo, C. and Schulze-Lefert, P. A novel class of eukaryotic zinc-binding proteins is required for disease resistance signalling in barley and development in C. elegans. (1999) Cell 99: 355-366.
 
Shirasu, K., Nielsen, K. A., Piffanelli, P., Oliver, R. and Schulze-Lefert, P. Cell-autonomous complementation of mlo resistance using a transient expression system in barley. (1999) Plant J. 17: 293-299.
 
Schulze-Lefert, P.M.J. Shirasu, K., Lahaye, T. A plant disease resistance signalling gene: materials and methods relating thereto PATENT WO2000008160 A3
 
1998
 
Shirasu, K. Genetic analysis of plant disease resistance. (1998) Plant Disease Resistance: A New Frontier in Plant Science ed. by Shimamoto, K. (in Japanese) 108-114. SYUJYUNSYA, Tokyo.
 
Lahaye, T., Shirasu, K. and Schulze-Lefert, P. Chromosome landing at the barley Rar1 locus. (1998) Mol. Gen. Genet. 260: 92-101.
 
1997
 
Shirasu, K., Nakajima, H., Rajasekhar, V. K., Dixon, R. A. and Lamb, C. Salicylic acid potentiates a gain-control amplifying pathogen signals for activation of plant disease resistance mechanisms. (1997) Plant Cell 9: 261-270.
 
1996
 
Jones, A. L., Lai, E-M., Shirasu, K. and Kado, C. I. (1996) VirB2 is a processed pilin-like protein encoded by the Agrobacterium Ti plasmid. J. Bacteriol. 178: 5706-5711.
 
Shirasu, K., Dixon, R. A. and Lamb, C. Signal transduction in plant immunity. (1996) Curr. Opin. Immunol. 8: 3-7.
 
Xu, Y., Zhu, Q., Panbangred, W., Shirasu, K. and Lamb, C. (1996) Regulation, expression and function of a new basic chitinase gene in rice (Oryza sativa L.). Plant Mol Biol. 30: 387-401.
 
1994
 
Jones, A. L., Shirasu, K. and Kado, C.I. (1994) The product of the virB4 gene of Agrobacterium tumefaciens promotes accumulation of VirB3 protein. J. Bacteriol. 176: 5255-5261.
 
Shirasu, K., Koukolikova-Nicola, Z., Hohn, B. and Kado, C.I. (1994) An inner-membrane associated protein essential for T-DNA transfer from Agrobacterium tumefaciens to plant exhibits ATPase activity and similarities to conjugative transfer genes. Mol. Microbiol. 11: 581-588.
 
1993
 
Shirasu, K. and Kado, C. I. (1993) Membrane location of the Ti plasmid VirB proteins involved in the biosynthesis of a pilin-like conjugative structure on Agrobacterium tumefaciens. FEMS Microbiol. Letters 111: 287-294.
 
Shirasu, K. and Kado, C. I. (1993) The virB operon of the Agrobacterium tumefaciens virulence regulon has sequence similarities to B, C, and D open reading frames down stream of the pertussis toxin operon and to the DNA transfer operon of broad-host-range conjugative plasmids. Nucleic Acids Res. 21: 353-354.
 
1990
 
*Shirasu, K., Morel, P. and Kado, C. I. (1990) Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis. Mol. Microbiol. 4(7): 1153-1163. PubMed
 
*Rogowsky, P. M., Powell, B. S., Shirasu, K., Lin, T.-S., Morel, P., Zyprian, E. M., Steck, T. R. and Kado, C. I. (1990) Molecular characterization of the vir regulon of Agrobacterium tumefaciens : Complete nucleotide sequence and gene organization of the 28.63-kbp regulon cloned as a single unit. Plasmid 23(2): 85-106. PubMed